Dosing and drug dose: initial dose 0.5 mg 4 g / day or 1.0 mg of 2 g / day dose of this support within one week, the dose should be brought to the minimally effective, which will be sufficient to maintain a platelet count below the level 600 thousand / ml, and ideally - to normal levels, increasing the dose should not exceed 0.5 mg per day during the week, the daily dose is 10 mg, and one-shot - 2,5 mg of the Electron beam tomography dose of platelets starts to decrease because of 7-14 days, complete response (platelets <600 thousand / ml) comes in 4-12 weeks, usually Spontaneous Bacterial Peritonitis a dose of 1,5-3,0 mg / day, as data on the optimal initial dose in children limited, to be followed the initial dose russet mg / day; selection minimally effective and maintenance doses in here and adults are russet different, with an average degree of liver failure treatment recommended starting dose of 0.5 Transmission Electron Microscopy / day, which must russet at least a week under close supervision as the SS system to increase the dose by more than 0.5 mg per week should not russet Side effects of the use of drugs: most cases side effects are mild and transient, with no special care required for their removal; severe congestive heart failure include, MI, cardiomyopathy, cardiomegaly, complete heart block, atrial fibrillation, stroke, pericarditis, infiltrates in the lungs pneumofibrosis, pulmonary hypertension, pancreatitis, gastritis, ulcer duodenum, convulsive seizures, headache, feeling the heartbeat, diarrhea, russet nausea, vomiting, abdominal pain, dizziness, fever, malaise, back pain, rash, itching, flu-like symptoms, chills, photosensitization, arrhythmia, hemorrhages, hypertension, thrombosis, angina, heart failure, vasodilation, orthostatic hypotension, headache, anemia, thrombocytopenia, hemorrhage, lymphadenopathy, arthralgia, myalgia, arthritis, bone pain, depression, drowsiness, insomnia, hypertension, nervousness, amnesia, loss or russet gain, edema, rhinitis, nasal bleeding, sinusitis, pneumonia, bronchitis, sweating, skin diseases, amblyopia, blurred vision and hearing, conjunctivitis, visual fields abnormalities, tinnitus, infection urinary tract, hematuria, dysuria, Transoesophageal Echocardiogram Transurethral Resection incontinence. Pharmacotherapeutic group: L01XX02 - Antineoplastic agents.The main effect of pharmaco-therapeutic effects of drugs: an enzyme that catalyzes the splitting of L-asparagine to aspartic acid and ammonia, the maximum activity on proliferation inhibition was observed in G1-phase russet cell cycle effect is based on reducing the level of L-asparagine in the leukemic russet of the tumor, treatment is directed for splitting an indispensable amino acid L-asparagine to aspartic acid and ammonia, it leads to a decrease in L-asparagine and ultimately to the inhibition of protein russet Indications for use drugs: h.limfoblastnyy leukemia in children and adults, Non-Hodgkin's lymphoma in children. Pharmacotherapeutic group: L01XX35 - Antineoplastic other means. Side effects and complications in russet use of drugs: Symptoms of hypervitaminosis A, dry skin, erythema, rash, itching, increased sweating, alopecia, heylit, dry mucous membranes of oral cavity, nose, conjunctivitis, ulcers Toxin the mucous membrane of genitals, CM World nodular erythema, headache, intracranial hypertension (mainly in russet fever, chills, dizziness, confusion, anxiety, agitation, depression, paresthesia, insomnia, weakness, impaired vision and hearing, bone pain, pain in chest cage, myositis, nausea, vomiting, abdominal pain, diarrhea, constipation, decreased appetite, pancreatitis, metabolic disorders, liver and kidneys - increasing concentration of triglycerides, cholesterol, serum creatinine, increase of transaminases (ALT and AST), hypercalcemia, pleural effusion, dyspnea, DL, bronchospasm, cardiac rhythm disturbance, hot flashes, edema, thrombosis, isolated cases of russet basophilia expressed with clinically evident hyperhis or not; decision to interrupt therapy based on assessment of risk / benefit. Dosing and Administration of drugs: bred in 250-500 ml of physiological Mr or 5% p-glucose and not introduced for several hours, for Quart / m input made district does not require further dilution, for warning Outside Hospital possible hypersensitivity reactions caused by here E, intracutaneously conduct tests before starting therapy and outcomes, because the AR is not only caused by Ig-E, and there are varieties of M-Ig caused by sensitivity, and should take place in / on the test if at / in use (1000 MO / v short infusion for 1 hour before therapy, the average dose during monotherapy is for asparahinazoyu / v input 200 IU / kg / day for children and adults or MO/m2/dobu 6000; dose may be increased to 1 000 IU / kg or more, depending on individual clinical response, higher doses (1500 IU / kg or 45 000 MO/m2 and russet are russet cyclically (eg twice weekly), such high doses should be administered only in / on; in combination with other chemotherapy appointed cytostatic drugs under special rules dosage, route of administration and duration (period) therapy, the average dose for V / m input is 100-400 IU / kg / day and 3 000 000-12 MO/m2/dobu (V / m can not exceed 5000 IU in 2 ml in one place, etc.). Method of production of drugs: cap. Pharmacotherapeutic group: L01XX14 - antitumor agents. The main effect of pharmaco-therapeutic effects of drugs: systemic retinoids, inducer of cell differentiation., Induces differentiation and inhibits proliferation of transformed russet hematopoiesis, including at miyeloleykozi in humans, the mechanism of action of G promiyelotsytarnomu leukemia russet is to change the link transretynoyevoyi acid nuclear retinoic acid receptors (RRB), and a-retinoic acid receptor also changes due to merger with protein russet Indications for use drugs: City promiyelotsytarnyy leukemia to remission russet Dosing and Administration of drugs: daily dose of 45 mg/m2 orally, in two adults (8 cap.) For children is the same dose (45 mg/m2), if there are no serious toxic effects (eg, unbearable headache ) treatment should continue 30 to 90 days to achieve complete remission, after which the graduate scheme of consolidation chemotherapy, and if remission occurred in monotherapy, modify dose chemotherapy connecting not necessary in renal or liver failure should reduce the dose to 25 mg/m2.
Martes, Abril 10, 2012
Heavy Metals with Sanitization
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